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姓 名:王 晶
性 别:女
职 称:研究员
学 历:博士
通讯地址:北京市朝阳区大屯路甲4号中科院心理所新东楼D401
电 话:010-6485 5021
邮政编码:100101
传 真:010-6485 5841
电子邮件:wangjing@psych.ac.cn
简历:
博士,研究员,博士生导师。于 2000 年获上海交通大学学士学位,2005 年获北京大学生物信息学博士学位,2005-2008 年任中国科学院北京基因组研究所副研究员,2008 年 6 月入选中国科学院心理研究所特聘研究员。王晶研究员从事以生物数据分析,算法设计和数据库开发为主的生物信息学和系统生物学研究,迄今在 Nature、Nucleic Acids Research、PLoS Comput Biol. 等国内外知名杂志上发表论文 30 多篇,影响因子总计为237分。2007 年被评为北京市科技新星。先后主持、参与多项国内外重大项目,包括 863、973 项目、自然科学基金、欧盟第六框架计划等。
课题组网页:http://bioinfo.psych.ac.cn/CN/index.jsp
研究领域:
1.复杂疾病的基因组学与表观基因组学研究
2.系统生物学与合成生物学
3.生物信息数据库的开发与构建
社会任职:
中国遗传学会 国际交流委员会 委员中国心理学会 委员
获奖及荣誉:
2003年获得由“北京防治非典型肺炎联合工作小组”颁发的首都防治“非典”工作纪念证书
2007年获得“北京市科技新星”称号
代表论著:
* 第一作者
# 通讯作者
1.Zhang, L.Y, Chang, S.H., Wang, J.# 2010. How to make a minimal genome for synthetic minimal cell. Protein & Cell. (In press)。
2.M. Vayssier-Taussat, D. Le Rhun, H.K. Deng, …, H.M. Yang, J. Wang, P. Engel, H. Saenz and C. Dehio. 2010. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS Pathogens. (In press)
3.Zhang, K.L, Cui, S.J., Chang, S.H., Zhang, L.Y., Wang, J.# 2010. i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study . Nucleic Acids Res; doi: 10.1093/nar/gkq324
4.Zhu, X.X, Chang, S.H., Fang, K.C., Cui, S.J., Liu, J., …, Wang, J# 2009. MyBASE: a database for genome polymorphism and gene function studies of Mycobacterium. BMC Microbiology. 9:40.
5.Nijssen E, Cescau S, Vayssier-Taussat M, Wang, J, Biville F. 2009. Identification of mechanisms involved in iron and haem uptake in Bartonella birtlesii: in silico and in vivo approaches. Clin Microbiol Infect.
6.He, X.M., Chang, S.H., Zhang, J.J., Zhao, Q., Xiang, H.Z., …, and Wang, J.#. 2008. MethyCancer: the database of human DNA methylation and cancer. Nucleic Acids Res. 36: D836-841.
7.Zhu, J., He, F.H., Song, S., Wang, J. #, Yu, J. 2008. How many human genes can be defined as housekeeping with current expression data? BMC Genomics. 9:172.
8.Zhu, J., He, F.H., Wang, J.# and Yu, J. 2008. Modeling Transcriptome Based on Transcript-Sampling Data. PLoS ONE. 3(2): e1659.
9.朱新星,罗永伦,王晶#,杨焕明。 2008. 合成生物学进展与应用。 国际遗传学杂志 第31卷 4期 281页 (ISSN: 1673-4386 CN: 23-1536/R )。
10.Chang, S. H., Zhang, J. J., Liao, X. Y., Zhu, X. X., Wang, D. H., …, and Wang, J.#. 2007. Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research. Nucleic Acids Res. 35: D376-380.
11.Chen, C., Tang, J., Dong, W., Wang, C., Feng, Y., Wang, J., Zheng, F., et al. 2007. A Glimpse of Streptococcal Toxic Shock Syndrome from Comparative Genomics of S. suis 2 Chinese Isolates. PLoS ONE. 2(3): e315. doi:10.1371/journal.pone.0000315.
12.Muzny, D.M., Scherer, S.E., Kaul, R., Wang, J., Yu, J., et al. 2006. The DNA sequence, annotation and analysis of human chromosome 3. Nature 440: 1194-1198.
13.Sorensen, M.D., Sorensen, B., Gonzalez-dosal, R., Melchjorsen, C.J., Weibel, J., Wang, J., Chen, W.J., Yang, H.M. and Kristensen, P. 2006. Severe Acute Respiratory Syndrome (SARS) Development of Diagnostics and Antivirals. Ann. N.Y. Acad. Sci. 1067: 500-505.
14.Ye J, Fang L, Zheng H, Zhang Y, Chen J, Zhang Z, Wang J, Li S, Li R, Bolund L, and Wang J. 2006. WEGO: a web tool for plotting GO annotations. Nucleic Acids Res. 34: W293-W297.
15.Wang, J.*, He, X.M., Ruan, J., Dai, M.T., Chen, J., et al. 2005. ChickVD: a sequence variation database for the chicken genome. Nucleic Acids Res. 33: D438-441.
16.Wang, J.*, Xia, Q.Y., He, X. M., Dai, M.T., Ruan, J., et al. 2005. SilkDB: a knowledgebase for silkworm biology and genomics. Nucleic Acids Res. 33: D399-402.
17.Wang, J.*, Zhang, M., Wu, Q.F., Huang W., Shen, Y., et al. 2005. 'Beijing Region' (3pter-D3S3397) of the Human Genome : Complete sequence and analysis. Science in China. 48. 311-329.
18.Li, R.Q., Ye, J., Li, S.G., Wang, J*., Han, Y.J., et al. 2005. ReAS: Recovery of ancestral sequences for transposable elements from the unassembled reads of a whole genome shotgun. PLoS Comp. Biol, 1: e43.
19.Yu, J., Wang, J., Lin, W., Li, S.G., Li, H., …, Wang, J., …, and Yang, H.M. 2005. The Genomes of Oryza sativa: A History of Duplications. PLoS Biol. 3(2): e38.
20.王晶*,张猛,吴清发等。 2005. 人类基因组北京区域(3pter-D3S3397):序列完成图与分析。 《中国科学》C辑-生命科学 .35: 286-303.
21.Zhao, W.M., Wang, J.*, He, X.M. Huang, X.B, Jiao, Y.Z., et al. 2004. BGI-RIS: an integrated information resource and comparative analysis workbench for rice genomics. Nucleic Acids Res. 32: D377-382.
22.Wong, K-S.G., Liu, B., Wang, J., Zhang, Y., Yang, X., …, Wang, J., …, and Hao, B.L. 2004. A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature. 432. 717-722.
23.Xia, Q., Zhou, Z, Lu, C., Cheng, D., Dai, F., …, Wang, J., …, and Yang, H. 2004. A draft sequence for the genome of domesticated silkworm (Bombyx mori)。 Science. 306: 1937-1940.
24.International Human Genome Sequencing Consortium (Wang, J. as an author from Beijing Genomics Institute)。 2004. Finishing the euchromatic sequence of the human genome. Nature. 431: 931-945.
25.韩玉军,倪培相,吕宏,叶葭,胡建飞, …, 王晶,…,李松岗。 2004. 正反向测序信息在全基因组序列拼接及分析中的应用。 《中国科学》C辑-生命科学 ISSN:1006-9259, 第34卷 第6期 :575-581.
26.Hu, J.F., Wang, J.*, …, Yang, H.M. 2003. Evolution and Variation of the SARS-CoV Genome. Geno., Prot., & Bioinfo. 1: 216-225.
27.Xu, J., Hu, J.F., Wang, J.*, …, Yang, H.M. 2003. Genome Organization of the SARS-CoV. Geno., Prot., & Bioinfo 1: 226-235.
28.Wu, Q.F., Zhang, Y.L., Lv, H., Wang, J.*… Yang, H.M. 2003. The E Protein Is a Multifunctional Membrane Protein of SARS-CoV. Geno., Prot., & Bioinfo. 1: 131-144.
29.Bi, S.L, Qin, E'de, Xu, Z.Y., Li, W., Wang, J.*,…Yang, H.M. 2003. Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)。 Geno., Prot., & Bioinfo 1: 180-192.
30.Li, J.X., Luo, C.Q. … Wang, J. … Yang, H.M. 2003. The Structural Characterization and Antigenicity of the S Protein of SARS-CoV, Geno., Prot., & Bioinfo.1: 108-117.
31.Hu, Y.W., Wen, J.…Wang, J… Yang, H.M. 2003. The M Protein of SARS-CoV: Basic Structural and Immunological Properties, Geno., Prot., & Bioinfo.1:118-130.
32.Qin, E'de, He, X.L. … Wang, J. … Yang. H.M. 2003. A Genome Sequence of Novel SARS-CoV Isolates: the Genotype, GD-Ins29, Leads to a Hypothesis of Viral Transmission in South China, Geno., Prot., & Bioinfo.1: 101-107.
33.Yu, J., Hu, S.N., Wang, J., Li, S.G., Wong, K-S.G., …, Wang, J, …, and Yang, H.M. 2002. A draft sequence of the rice genome (Oryza sativa ssp. Indica), Science, 296, 79-92.
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